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Beautiful Landscape

Research

We focus on the application of micro/nanotechnology to enhance the performance of assays or the functionality of bioactive compounds. 

我們專注於將微/納米技術應用於提高檢測方法的性能或增強生物活性物質的功能性

1. Developing assays for detecting food allergens

 建立檢測食品過敏原的方法

Food allergy has become a global issue. For protecting patients from the accidental ingestion of food allergens, it is urgently needed to develop assays for detecting food allergen residues in foods. In our group, we have worked on establishing various assays to detect common allergenic foods, including peanut, sesame, wheat, kiwi, and mango. The assays we currently investigate are LC-MS/MS, lateral flow assay, electrochemical immunoassays, real-time PCR and LAMP.       

​​食物過敏已經成為全球性的問題。為了保護患者免受食物過敏原的意外攝入,迫切需要開發檢測食物中過敏原殘留的檢測方法。在我們的團隊中,我們已經開展了建立各種檢測方法以檢測常見的過敏性食物,包括花生、芝麻、小麥、奇異果和芒果。我們目前研究的檢測方法包括液相色譜質譜儀(LC-MS/MS)、側向流動免疫層析試驗、電化學免疫分析、即時聚合酶鏈反應和LAMP。

2. Developing assays for detecting food pathogens

 建立檢測食品病原菌的方法

The contamination of food pathogens is the leading cause of foodborne illness in Taiwan, and the common food pathogens are Vibrio parahaemolyticus, Staphylococcus aureus, and Bacillus cereus. In our group, we have worked on developing rapid assays for identifying these food pathogens and bacterial toxins in foods.

食品病原菌污染是台灣食品中引起食源性疾病的主要原因,常見的食品病原菌有副溶血性弧菌、金黃色葡萄球菌和仙人掌桿菌。我們的研究小組致力於開發快速檢測方法,以便在食品中檢測這些食品病原菌和細菌毒素。    

3. Using liposomal nanoparticles to enhance the functionality of bioactive compounds

使用脂質體奈米粒子來增強生物活性物質的功能性  

Liposomal nanoparticles are made by lipid bilayers with a large cavity to encapture a large number of biomolecules.  The lipid bilayers can offer a barrier to protect biomaterials from harsh environmental conditions, leading to liposomal nanoparticles being a good nanocarrier. In our groups, we have utilized liposomal nanoparticles to encapsulate ginseng extract to enhance its anti-oxidative damage and to encapsulate berberine to improve its anticancer activity against hepatoma.

脂質體奈米粒子是由脂質雙層構成的,具有一個大的空腔,可容納大量的生物分子。脂質雙層可以提供一個屏障,保護生物材料免受惡劣環境條件的影響,因此脂質體奈米粒子是一種良好的奈米載體。在我們的研究小組中,我們利用脂質體奈米粒子封裝人蔘提取物,以增強其抗氧化損傷的效果,並將小檗鹼封裝於其中,以提高其對肝癌的抗癌活性。

4. Studying the safety and functionality of biomolecules from natural sources

研究來自天然來源的生物分子的安全性和功能性

Nowadays, people prepare to use materials from natural resources than synthetic compounds. Therefore, we have worked on realizing the safety and functionality of some herbal medicines originally from Taiwan, including the flower extract of Koelreuteria henryi Dummer, and the water extract of tissue-cultured Taraxacum formosanum and Lignosus rhinocerus

現今人們更傾向於使用來自天然資源的材料,而非合成化合物。因此,我們致力於實現一些來自台灣的草本藥材的安全性和功能性,包括欒樹花萃取物、組織培養蒲公英和虎乳靈芝水萃取物。
 

超級健康食品
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